2025
Autoradiographic comparison between [¹¹C]PiB and [¹⁸F]AZD4694 in human brain tissue
EJNMMI Research
Autoradiography
Preclinical Imaging & Molecular Analysis
Advanced imaging, quantitative analysis and molecular characterization for translational research and radiotracer development.
At ModivioBio, we provide advanced preclinical imaging and molecular analysis solutions to support translational research and radiotracers development. Our integrated platform combines state-of-the-art imaging technologies with rigorous quantitative analysis, enabling researchers to investigate disease mechanisms, evaluate radiotracer candidates, and accelerate the path toward clinical translation.
Our multidisciplinary scientific team works closely with academic investigators and biopharmaceutical partners to design robust, customized preclinical studies tailored to specific research objectives.
Services
Core service areas from ModivioBio’s preclinical imaging and molecular analysis platform.
Preclinical PET Imaging
Preclinical positron emission tomography (PET) imaging for molecular and functional processes in vivo.
Preclinical MRI Imaging
Magnetic resonance imaging (MRI) for high-resolution anatomical and functional imaging without ionizing radiation.
Radiotracer Biodistribution Studies
Quantitative tissue distribution, uptake, and clearance of radiolabeled molecules.
Autoradiography Imaging
High-sensitivity localization of radiolabeled compounds in biological samples.
Image Processing and Analysis
Image processing and analysis for PET, CT, MRI and Autoradiography data, including data quantification and kinetic modeling.
Consultation and Study Design
Consultation for study design, protocol development, and data interpretation.
Image Processing and Analysis includes Data Quantification and Kinetic Modeling as described in the source materials.
Scientific evidence
Actual imaging and analysis outputs: molecular imaging, quantitative networks, and translational autoradiography. Figures are cropped from scientific materials (presentation titles and logos removed). Scales and legends that carry scientific meaning are preserved. These are capability illustrations, not published client study results.
Molecular Imaging
Quantitative Analysis
Translational Research
![Autoradiography comparison of [¹⁸F]Flortaucipir, [¹⁸F]MK6240, and [¹⁸F]PI2620 in Control versus AD whole-brain hemisphere sections.](https://modiviobio.com/wp-content/themes/modivio/assets/images/evidence/autoradiography-tracers-control-ad.jpg)
Why choose ModivioBio
At ModivioBio, we combine scientific excellence, advanced imaging technologies, and deep expertise in translational research to deliver high-quality preclinical data that supports confident decision-making in drug development.
We specialize in preclinical imaging, data processing, and quantitative analysis in animal models, leveraging advanced PET, MRI and Autoradiography technologies. Our experienced scientific team designs and executes rigorous preclinical studies tailored to each client’s research objectives
Scientific Leadership
Our organization is led by internationally recognized scientists whose work has significantly contributed to the advancement of preclinical imaging and biomedical research. Our Scientific Advisory Board and founder have collectively authored more than 740 peer-reviewed publications, reflecting decades of scientific innovation and leadership.
Pedro Rosa-Neto MD, PhD
Scientific Advisory Board · more than 550 peer-reviewed publications
Dr. Rosa-Neto is a clinical neurologist with over 25 years of experience in advanced brain imaging techniques, specializing PET and MRI to investigate and quantify neurological changes.
Eduardo Zimmer PhD
Scientific Advisory Board · more than 150 peer-reviewed publications
Dr. Zimmer is an internationally recognized expert in neurodegenerative disease, with a primary focus research focuses on neuro-to-astrocyte communication, brain energy metabolism and neuroimaging.
Antonio Aliaga, PhD
Founder · more than 40 peer-reviewed papers
Dr. Aliaga is a founder of ModivioBio and has more than 26 years of experience in the development of PET, SPECT, CT, MRI, and autoradiographic techniques.
Publications
Selected papers from the scientific record. Titles, authors, journals, and links are entered only from published sources.
Discuss your preclinical imaging study
Tell us about your research question and we will connect you with the appropriate scientific expertise. Contact is human-mediated — no automated study intake, ecommerce checkout, client portal, or AI assistant.