Preclinical Imaging & Molecular Analysis

Advanced imaging, quantitative analysis and molecular characterization for translational research and radiotracer development.

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At ModivioBio, we provide advanced preclinical imaging and molecular analysis solutions to support translational research and radiotracers development. Our integrated platform combines state-of-the-art imaging technologies with rigorous quantitative analysis, enabling researchers to investigate disease mechanisms, evaluate radiotracer candidates, and accelerate the path toward clinical translation.

Our multidisciplinary scientific team works closely with academic investigators and biopharmaceutical partners to design robust, customized preclinical studies tailored to specific research objectives.

Services

Core service areas from ModivioBio’s preclinical imaging and molecular analysis platform.

Preclinical PET Imaging

Preclinical positron emission tomography (PET) imaging for molecular and functional processes in vivo.

Preclinical MRI Imaging

Magnetic resonance imaging (MRI) for high-resolution anatomical and functional imaging without ionizing radiation.

Radiotracer Biodistribution Studies

Quantitative tissue distribution, uptake, and clearance of radiolabeled molecules.

Autoradiography Imaging

High-sensitivity localization of radiolabeled compounds in biological samples.

Image Processing and Analysis

Image processing and analysis for PET, CT, MRI and Autoradiography data, including data quantification and kinetic modeling.

Consultation and Study Design

Consultation for study design, protocol development, and data interpretation.

Image Processing and Analysis includes Data Quantification and Kinetic Modeling as described in the source materials.

Scientific evidence

Actual imaging and analysis outputs: molecular imaging, quantitative networks, and translational autoradiography. Figures are cropped from scientific materials (presentation titles and logos removed). Scales and legends that carry scientific meaning are preserved. These are capability illustrations, not published client study results.

Molecular Imaging

Quantitative Analysis

Autoradiography across tau radiotracers in control and

Translational Research

Autoradiography comparison of [¹⁸F]Flortaucipir, [¹⁸F]MK6240, and [¹⁸F]PI2620 in Control versus AD whole-brain hemisphere sections. — Autoradiography across tau radiotracers in control and AD conditions. Antonio Aliaga et al. JNM, 2024

Why choose ModivioBio

At ModivioBio, we combine scientific excellence, advanced imaging technologies, and deep expertise in translational research to deliver high-quality preclinical data that supports confident decision-making in drug development.

We specialize in preclinical imaging, data processing, and quantitative analysis in animal models, leveraging advanced PET, MRI and Autoradiography technologies. Our experienced scientific team designs and executes rigorous preclinical studies tailored to each client’s research objectives

Scientific Leadership

Our organization is led by internationally recognized scientists whose work has significantly contributed to the advancement of preclinical imaging and biomedical research. Our founder and Scientific Advisory Board have collectively authored more than 740 peer-reviewed publications, reflecting decades of scientific innovation and leadership.

Antonio Aliaga, PhD

Founder · more than 40 peer-reviewed papers

Dr. Aliaga is a founder of ModivioBio and has more than 26 years of experience in the development of PET, SPECT, CT, MRI, and autoradiographic techniques.

Pedro Rosa-Neto, MD, PhD

Scientific Advisory Board · more than 550 peer-reviewed publications

Dr. Rosa-Neto is a clinical neurologist with over 25 years of experience in advanced brain imaging techniques, specializing PET and MRI to investigate and quantify neurological changes.

Eduardo Zimmer, PhD

Scientific Advisory Board · more than 150 peer-reviewed publications

Dr. Zimmer is an internationally recognized expert in neurodegenerative disease, with a primary focus research focuses on neuro-to-astrocyte communication, brain energy metabolism and neuroimaging.

Founder and Scientific Advisory Board

References

Selected papers from the scientific record. Titles, authors, journals, and links are entered only from published sources.

2025

Autoradiographic comparison between [¹¹C]PiB and [¹⁸F]AZD4694 in human brain tissue

Aliaga A, Therriault J, Quispialaya K, Aliaga A, Kunach P, Macedo AC, Hopewell R, Rahmouni N, Soucy JP, Massarweh G, Guiot MC, Chan T, Klostranec J, Abreu Diaz AM, Rocha A, Carello-Collar G, Machado LS, De Bastiani MA, Guerini de Souza D, Souza DO, Zimmer AR, Gauthier S, Pascoal TA, Zimmer ER, Rosa-Neto P.

EJNMMI Research

Autoradiography

10.1186/s13550-025-01216-8 PubMed Publication

View all references

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